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KMID : 0613820100200071034
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Journal of Life Science
2010 Volume.20 No. 7 p.1034 ~ p.1040
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The Effect of Aster glehni Fr. Schm. Extracts on Whitening and Anti-Wrinkle
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Kim Han-Hyuk
Park Gun-Hye
Park Kang-Soo
Lee Jin-Young
Kim Tae-Hoon
An Bong-Jeun
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Abstract
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Plants and their extracts can be utilized as inexpensive and rich resources of active constituents in the cosmetic field, as well as the food, pharmaceutical and medicinal fields. Until now, Aster glehni Fr. Schm. had no known active effect, except on anti-oxidation, that was found during investigations for application in the cosmetic field. In this study, we examined the inhibition of enzymatic reactions to protein levels in inclusive B16F10 melanoma cell lines. Significant inhibition of enzymatic reactions was observed in the EtOAc extract, which advanced to tyrosinase protein and TRP-1 in the B16F10 melanoma cell line. These results indicated that the effect of EtOAc extract inhibited expressions of tyrosinase protein and TRP-1 in the B16F10 melanoma cell line by 30.5% and 41.5% at 100㎍/㎖ respectively. On the other hand, antimicrobial activity was evaluated to the four fractions in normal flora of the skin. Hexane extract was only exhibited in the higher clear zone in all strains. In conclusion, any cosmeceutical effects of Aster glehni Fr. Schm. may have a potential meaning, as well as possible value for further studies regarding the effects of chemical constituents of Aster glehni Fr. Schm.
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KEYWORD
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Whitening effect, anti-wrinkle effect, Aster glehni Fr. Schm
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